Knowledge & Technology Transfer

Technology transfer is the process of transferring scientific findings from one organisation to another for the purpose of further development and commercialisation.
The process followed typically includes:
– Identifying new technologies
– Protecting technologies through patents and copyrights
– Forming development and commercialisation strategies such as marketing and licensing to existing private sector companies or creating new startup companies based on the technology.

The ultimate benefits of technology transfer are the public benefits derived from the products that reach the market and the jobs that result from the development and sale of products

Academic and research institutions engage in technology transfer for a variety of reasons, such as:
– Recognition for discoveries made at the institution
– Compliance with regulations
– Attraction and retention of talented faculty
– Local economic development
– Attraction of corporate research support
– Licensing revenue to support further research and education

Commercialisation can be pursued without disrupting the core values of publication and sharing of information, research results, materials and know-how

The patenting by academic institutions of discoveries resulting from research protects the investment made in research and ensures that these discoveries have the opportunity to reach the stream of commerce. Investments in intellectual property are returned to the public through products that benefit the public, increased employment, and taxes. As the transition from a manufacturing-based economy to a knowledge-based economy continues, the role of university intellectual property will play an increasingly important part. Many countries are developing programs to enhance economic development through technology transfer from local research universities. This growing emphasis on economic development will undoubtedly lead to more complicated relationships, interactions and expectations for academic institutions.

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Technology transfer is the tool that helped translate a basic research discovery into products that have improved human health, and shaped our world

Sometimes, though, university discoveries require extensive development before products and services can be made available to the public. Universities can’t do this alone. In one of the major advances of the 20th century, researchers at Stanford and UC San Francisco learned to clone genes in the early 1970s, but it wasn’t until 1982 that the first new drug based on this discovery – human insulin – was approved for human use. Turning the research discovery into a useful product required significant investment and further development by a private company partner, Genentech. Because companies invested in developing this university discovery, today literally hundreds of new health care products are in use, and a new industry – biotechnology – adds tremendous value to the world’s economy.

Institutions support their technology transfer programs, and many programs must be self-supporting. Most of the funds generated through technology transfer go for further research and education, and are shared with researchers who often use them for additional research

Everyone, it seems, has an idea of what technology transfer can do for them. In this environment, the people who manage the university innovations play a crucial role and are relied upon by universities, companies, investors and economic development officials to identify and manage new discoveries in the best interest of the public. Their role includes:
• Preserving intellectual property rights
• Facilitating partnerships with companies and other partners in support of further research or product development
• Protecting the academic research enterprise – the source of future innovations.

We invite you to learn more about products and some of the exciting stories behind successful technology transfer efforts

In the summer of 2006, specialists from a dozen leading research institutions came together to consider the role of technology transfer in today’s university. Recognising that, “universities share certain core values that can and should be maintained to the fullest extent possible in all technology transfer agreements,” they discussed their shared perspectives on the profession and developed “Nine Points to Consider in Licensing University Technology”. Among the values supported are scientific freedom, broad access to research tools, conflicts of interest, and unmet societal needs. The role of technology transfer will be critical for universities for the foreseeable future.

Paradigms of current Knowledge and Technology Transfer projects (under interdisciplinary Scientific collaboration with NTUA)- HESTIA
House/building with minimized Energy requirements with Sensors & Transducers with Intelligence and Autonomy
+ The project refers to the development and implementation of a novel and innovative methodology for the house or building of the next century. Such a house has to offer minimized energy requirements, zero or minus energy demand, as well as intelligent sensor systems, offered at a respectfully low cost of development (The project allows the consortium for a profit before taxes in the order of €810Μ)

- (ADIT) Advanced Diagnostics & Therapeutics. ADIT aims at developing biosensors and diagnostic tools, in the form of impedance sensors, optic instruments and electromagnetic – magnetic sensors, as well as therapeutic methodologies like skin cancer treatment, magnetically aided targeted drug delivery and electromagnetic stimulation. Apart from that, the know-how extends to other technologies in the field of agriculture. Briefly, these technologies are summarized in the following:

+ Biosensors & diagnostic tools
Development of biosensors, namely blood, urine and saliva testers for parametric measurement of ingredients, viruses etc, including wearables for Troponin-T detection. Furthermore, there has been developed technology on an optical instrument to detect fluorescence, absorption and scattering in a wide range of wavelengths, from 280nm to 1200nm. Currently, there is development of plasmonic films to amplify and therefore to detect bio-molecular compounds with emphasis on skin cancer, ingredients in agricultural products such as olive oil, wine and honey, as well as continuous emission monitoring from exhausts. Finally, the electromagnetic sensors refer to the distant monitoring of diseases of different tissues and/or organs based on the change of the resonance frequency of the given tissue or organ

+ Therapeutic methodologies
Therapeutic methods refer to various technologies. At first, skin cancer can be treated on surfaces where the optical instrument has detected tumour cells by using a special cream that, in the presence of light and oxygen, generates oxidized molecules that preferably cause apoptosis and necrosis of tumour cells without affecting the healthy tissues. The method can also be applied in bowel cancer. The second method is the magnetically aided targeted drug delivery, provided that the tumour is not distributed in the blood. The carriers of the drug are magnetic micro-algae (micro-algae with magnetic nanoparticles). Then, the gradient field concentrates all magnetic micro-algae at the volume(s) of interest, where a localized electric field releases the drug but not the magnetic nanoparticles. Thus, the drug is locally delivered, killing any cell, with the magnetic micro-algae to move through urine. The last therapeutic method is related to electromagnetic stimulation, according to which pulsed electromagnetic fields try to rehabilitate the stereo-structure of proteins, a matter of observation in Cryo-TEM. Initial work concerns treatment of multiple sclerosis

+ Other future products
Agriculture and drinkable water are two major issues in developed and under-developed countries. The quantity and the quality of plants is of critical importance due to the vast increase of population. The Lab participates in the development and dissemination – exploitation of the treatment of agricultural wastes, such as olive oil and wine wastes, that after undergoing a compost process, are further treated to become biological horticulture humus soil, which is used as fertilizer offering 3X increase of production and 5X-7X increase of the quantity of ingredients in these products. The technology is currently selling in about 20 countries worldwide, with relatively small exploitation results. Humus soil can also be used in greenhouses, allowing for sustainable productivity of excellent quality plants, thus allowing for proper certification and packaging (from the field to the shelf). Finally, the lab has initiated its selective magnetic separation, permitting the trapping of different heavy ions on the surface of magnetic particles covered by crown ethers. Furthermore, the lab is continuously studying the water's properties and methods to make it drinkable

Paradigms of current Knowledge and Technology Transfer projects (under interdisciplinary Scientific collaboration with NTUA). More information may be given to potential collaborators and investors under a confidentiality agreement. Formally contact the director of the institute Dr. Harry Paterakis: hp@SR21.ch

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The motivation for most people in technology transfer is not the money it can generate. The real value is about impact

The main motivation for a university to transfer technology is an extension of its basic mission – to teach, to generate and share new knowledge, and to be of service to society. And sometimes technology transfer generates significant income for the company partner and the university. With increasing success, and the occasional blockbuster product based on an academic discovery, reliance on university technology transfer efforts has grown. Regionally, universities are seen as a source of innovations for local companies to create new products and local jobs. University officials see technology transfer activities as a potential source of revenue to support university programs, and an opportunity for professional development for faculty keen to see their research benefit the public.

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